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Choosing to use addEventListener over onclick is often based on the following factors:

1. Multiple Listeners: addEventListener allows you to attach multiple event handlers to the same event without overwriting existing ones. With onclick, if you set a new function, it replaces the previous one.

   // Using addEventListener
   element.addEventListener('click', handler1);
   element.addEventListener('click', handler2); // Both handlers will run
   
   // Using onclick
   element.onclick = handler1;
   element.onclick = handler2; // Only handler2 will run
   

2. Event Options: addEventListener provides more control through options like capture, once, and passive that can optimize performance and behavior. For example, you can tell the listener to capture events in the capturing phase or run only once.

   element.addEventListener('click', handler, { once: true }); // Runs once and removed
   

3. Better Separation: Using addEventListener promotes a cleaner separation of JavaScript and HTML, especially if you’re building larger applications. It keeps your HTML free of inline event handlers.

4. Compatibility: addEventListener is more versatile and consistent across different types of events, including custom events.

5. Event Object: The event object passed to the event handler is richer when using addEventListener, allowing access to properties and methods that are useful for event handling.

In summary, addEventListener is preferred for its flexibility, ability to manage multiple listeners, option for advanced features, and it encourages better coding practices.